Gypsogenic Acid (Synonyms: Astrantiagenin J) |
カタログ番号GC49837 |
抗菌およびトリパノシダル活性を持つ三萜酸
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Cas No.: 5/5/5143
Sample solution is provided at 25 µL, 10mM.
Gypsogenic acid is a triterpene acid that has been found in M. stenostachya and has antibacterial and trypanocidal activities.1,2 It is active against the oral bacterial pathogens E. faecalis, S. salivarius, S. sanguinis, S. mitis, S. mutans, and S. sobrinus (MICs = 50-200 µg/ml).1 Gypsogenic acid induces lysis of T. cruzi in isolated mouse blood (IC50 = 56.6 µM).2
1.Cunha, L.C.S., e Silva, M.L.A., Furtado, N.A.J.C., et al.Antibacterial activity of triterpene acids and semi-synthetic derivatives against oral pathogensZ. Naturforsch. C. J. Biosci.62(9-10)668-672(2007) 2.Cunha, W.R., Martins, C.H., da Silva, F., D., et al.In vitro trypanocidal activity of triterpenes from Miconia speciesPlanta Med.69(5)470-472(2003)
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