BAY-179 |
| カタログ番号GC49901 |
BAY-179 は、強力で選択的な種交差反応性の複合体 I 阻害剤です (IC50=79 μM)。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2764880-87-5
Sample solution is provided at 25 µL, 10mM.
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BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively).1 See the Structural Genomics Consortium (SGC) website for more information.
1.Mowat, J., Ehrmann, A.H.M., Christian, S., et al.Identification of the highly active, species cross-reactive complex I inhibitor BAY-179ACS Med. Chem. Lett.13(3)348-357(2022)
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