Ac-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt) (Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO, Caspase-8 Inhibitor I) |
| カタログ番号GC40118 |
Ac-AAVALLPAVLLALLAP-IETD-CHOは、カスパーゼ-8のペプチド阻害剤であるAc-IETD-CHOと、K-FGFから派生した細胞浸透性疎水性配列の複合体です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO , a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF. It is an inhibitor of both caspase-8 and granzyme B. It prevents death of SKOV3 ovarian carcinoma cells transfected with Survivin and granzyme B-induced apoptosis (SAGA) when used at a concentration of 20 µM.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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