15(R)-Prostaglandin I2 (sodium salt) (Synonyms: 15(R)-PGI2) |
| カタログ番号GC41923 |
15(R)-プロスタグランジンI2（15(R)-PGI2）は、天然の15(S)プロスタノイドであるPGI2の異性体です。
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Sample solution is provided at 25 µL, 10mM.
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15(R)-Prostaglandin I2 (15(R)-PGI2) is an isomer of the natural 15(S) prostanoid, PGI2 . PGI2 is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 value of 5 nM. While the physiological properties of 15(R)-PGI2 are not well known, 15(R) isomers of PGs typically have reduced receptor agonist activity compared to their 15(S) forms.
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