15(S)-HETE-biotin (Synonyms: 15(S)-Hydroxyeicosatetraenoic Acid-biotin) |
カタログ番号GC41926 |
15(S)-HETEは、15-リポキシゲナーゼ経路によって生成される主要なアラキドン酸代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
15(S)-HETE is a major arachidonic acid metabolite produced by the 15-lipoxygenase pathway. It has been characterized as a potent inhibitor of 5-lipoxygenase. The mechanism by which 15(S)-HETE acts as a leukotriene inhibitor is not clear. In studies with P-18 mast/basophil cells, it was shown that specific 15-HETE receptors, rather than esterification, appeared to be involved in signal transduction. 15(S)-HETE-biotin can be used to detect 15(S)-HETE binding proteins and/or receptors.
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