3-Bromotyrosine-13C9,15N (trifluoroacetate salt) (Synonyms: 3-bromo-Tyr-13C9,15N) |
| カタログ番号GC42252 |
3-ブロモチロシン-13C9,15Nは、GCまたはLC-MSによる3-ブロモチロシンの定量のための内部標準として使用することを目的としています。
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Sample solution is provided at 25 µL, 10mM.
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3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS. 3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo. In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation. In a human study, 3-bromotyrosine was increased in allergen-challenged lung samples from subjects with allergen-induced asthma.
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