Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) (Synonyms: Acetyl Pituitary Adenylate Cyclase-activating Peptide (1-38)) |
| カタログ番号GC42699 |
アセチル下垂体腺腺病原性サイクラーゼ活性化ペプチド（PACAP）（1-38）は、N末端がアセチル化されたPACAP（1-38）の形態です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38) . It binds to the PACAP receptor PAC1 (IC50 = 5.6 nM for the human receptor) and induces calcium mobilization and proliferation of PC12 cells (EC50s = 4.4 and 0.83 nM, respectively) with an efficacy comparable to PACAP (1-38). Acetyl PACAP (1-38) is resistant to degradation by dipeptidyl peptidase 4 (DPP-4) with a 10-fold longer half-life than PACAP (1-38), respectively.
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