D-myo-Inositol-4,5-diphosphate (sodium salt) (Synonyms: Ins(4,5)P2 (sodium salt), 4,5IP2 (sodium salt)) |
| カタログ番号GC43539 |
D-ミオイノシトール-1,4,5-トリフォスフェート（Ins（1,4,5）P3）は、リン脂質であるリン酸イノシトール-4,5-二リン酸のPLCによる加水分解によって細胞内で生成される重要な第2メッセンジャーです。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a key second messenger produced in cells by PLC-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to one of several Ins(1,4,5)P3 receptors results in opening of the calcium channels and an increase in intracellular calcium. Ins(4,5)P2 is a metabolite of Ins(1,4,5)P3 that lacks a phosphate at the 1' position. Ins(4,5)P2 formation has been reported as an intermediate in the metabolism Ins(1,4,5)P3 in GH3 pituitary cells.
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