PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) (Synonyms: Phosphatidylinositol3,5diphosphate C16) |
カタログ番号GC44757 |
リン酸イノシトール(PtdIns)リン酸脂質は、全体の膜リン脂質のわずかな割合を占めています。
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Sample solution is provided at 25 µL, 10mM.
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions. PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.
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