PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) (Synonyms: DPPI4,5P2, Phosphatidylinositol4,5diphosphate C16) |
| カタログ番号GC44765 |
リン酸イノシトール（PtdIns）リン酸脂質は、全体の膜リン脂質のわずかな割合を占めています。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns PtdIns-(4,5)-P2 (1,2-dipalmitoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The natural compound is the product of PtdIns-4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
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