YVAD-CHO (trifluoroacetate salt) (Synonyms: H-Tyr-Val-Ala-Asp-CHO) |
| カタログ番号GC45175 |
YVAD-CHOは、caspase-1/interleukin-1β変換酵素（ICE）の阻害剤であり、Ac-YVAD-CHOの非アセチル化形です。
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Sample solution is provided at 25 µL, 10mM.
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YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO . It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan in 4B1 cells when used at a concentration of 600 µM. YVAD-CHO (100 µM) also prevents chromogranin A-induced cell death of primary rat microglia but not primary rat cerebellar granule neurons.
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