CAY10647 |
カタログ番号GC18901 |
CAY10647は、多剤耐性があるがん細胞の増殖を防止するアリール-ベンゾイル-イミダゾールであり、in vitroではIC50値が28〜63 nMであり、in vivoではメラノーマ移植腫瘍の成長を抑制します(10〜30 mg / kg)。
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Cas No.: 1253697-49-2
Sample solution is provided at 25 µL, 10mM.
CAY10647 is an aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg). This compound also binds to tubulin (Ki = 3.4 μM) and prevents tubulin polymerization.
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Average Rating: 5
(Based on Reviews and 9 reference(s) in Google Scholar.)Review for CAY10647
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