CD38 inhibitor 1 (Synonyms: CD38-IN-78c, CD38 Inhibitor 78c) |
| カタログ番号GC64948 |
CD38 インヒビター 1 (化合物 78c) は、hCD38 およびマウス CD38 に対して 7.3 nM および 1.9 nM の IC50 を持つ強力な CD38 インヒビターです 。
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Cas No.: 1700637-55-3
Sample solution is provided at 25 µL, 10mM.
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CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38[1].
CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle[1].
[1]. Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71.
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