CompK (Synonyms: compound K) |
| カタログ番号GC25289 |
CompK（コンパウンドK）は、強力で選択的な造血前駆細胞キナーゼ1（HPK1またはMAP4K1）小分子阻害剤であり、人間のT細胞機能を著しく改善し、腫瘍関連抗原を認識するためのT細胞受容体親和性が向上し、CD8 + T細胞による腫瘍溶解活性が増強されます。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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CompK (compound K), a potent and selective hematopoietic progenitor kinase 1 (HPK1 or MAP4K1) small molecule inhibitor, significantly improves human T-cell functions, with enhanced T-cell receptor avidity to recognize tumor-associated antigens and tumor cytolytic activity by CD8+ T cells.
[1] You D, et al. J Immunother Cancer. 2021 Jan;9(1):e001402.
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