D-myo-Inositol-1,4,6-triphosphate (sodium salt) (Synonyms: Ins(1,4,6)P3, 1,4,6IP3) |
| カタログ番号GC43524 |
D-ミオイノシトール-1,4,6-リン酸（Ins（1,4,6）-P3）は、細胞信号の伝達において小さな可溶性第二メッセンジャーとして重要な役割を果たすイノシトールリン酸（InsP）ファミリーの一員です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 157380-18-2
Sample solution is provided at 25 µL, 10mM.
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D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,4,6)-P3 (tested as the meso compound) is 9-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
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