Emamectin B1a (Synonyms: L-656,748) |
| カタログ番号GC18890 |
エマメクチンB1aはアベルメクチンB1aの半合成誘導体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 121124-29-6
Sample solution is provided at 25 µL, 10mM.
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Emamectin B1a is a semi-synthetic derivative of avermectin B1a . It binds to GABAA receptors (Ki = 17.6 nM in rat brain membranes), including those containing β1, β2, or β3 subunits (IC50s = 57, 210, and 49.8 nM for α1β1γ2, α1β2γ2, and α1β3γ2 subunits, respectively), and potentiates the GABA response. Emamectin B1a also binds to and inhibits glycine receptors (IC50 = 218 nM in rat spinal cord). Emamectin B1a induces mortality in 90% of S. exigua larvae in a diet incorporation assay at a dose of 1.067 ng/ml, which is approximately 1,500-fold more toxic than avermectin B1. It is effective against neonate S. eridania larvae in a foliage spray bioassay and when applied topically.
Review for Emamectin B1a
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
Review for Emamectin B1a
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