Ethylenediaminetetraacetic acid sodium hydrate (Synonyms: EDTA sodium hydrate) |
| カタログ番号GC67534 |
エチレンジアミン四酢酸 (EDTA) ナトリウム水和物は金属キレート剤 (カルシウムを含む金属の 2 価および 3 価陽イオンに結合) であり、抗凝固剤および抗高カルシウム血症の活性を示します。エチレンジアミン四酢酸ナトリウム水和物は、金属イオン触媒によるタンパク質の酸化損傷を軽減し、タンパク質精製時の還元環境を維持することができます。エチレンジアミン四酢酸ナトリウム水和物も、ジスルフィド結合の形成を減少させることができます。
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Cas No.: 10378-23-1
Sample solution is provided at 25 µL, 10mM.
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Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can also decrease the formation of disulfide bonds[1][2][3].
[1]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.
[2]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.
[3]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.
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