FA-Ala-Lys-OH |
カタログ番号GA21434
One-Click Copy Product Info
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FA-Ala-Lys-OHはポリペプチド化合物であり、酵素の活性スクリーニングと薬物の研究に使われる。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 76079-03-3
Sample solution is provided at 25 µL, 10mM.
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FA-Ala-Lys-OHはポリペプチド化合物であり、酵素の活性スクリーニングと薬物の研究に使われる[1]。FA-Ala-Lys-OHはよく酵素活性測定の基質として使われ、よって疎水性P'1アミノ酸残基に対するカルボキシペプチダーゼの選好速度論を調査する[1]。FA-Ala-Lys-OHはよく、アスペルギルス・ニガーで二種類のセリンカルボキシペプチダーゼ（CPD-IとCPD-II）を特徴づけるための基質として使われ、ArgとLysの特異性を調査した[2]。FA-Ala-Lys-OHは基質として使われ、ペニシリウム・ジャンシネラム由来のCarboxypeptidase S-1のエステル化反応を特徴づけ、エタノールを求核剤にし、特異性をテストした[3]。FA-Ala-Lys-OHは基質として使われ、麦芽カルボキシペプチダーゼIIの触媒加水分解反応速度のパラメータに対する、フェニルグアニジン水素炭酸塩とNaClの影響を調査する[4]。
References:
[1]Sørensen S B, Breddam K. The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 binding pocket[J]. Protein science, 1997, 6(10): 2227-2232.
[2]Dal Degan F, Ribadeau-Dumas B, Breddam K. Purification and characterization of two serine carboxypeptidases from Aspergillus niger and their use in C-terminal sequencing of proteins and peptide synthesis[J]. Applied and Environmental Microbiology, 1992, 58(7): 2144-2152.
[3]Breddam K. Carboxypeptidase S-1 from Penicillium janthinellum: enzymatic properties in hydrolysis and aminolysis reactions[J]. Carlsberg Research Communications, 1988, 53: 309-320.
[4]Breddam K. Enzymatic properties of malt carboxypeptidase II in hydrolysis and aminolysis reactions[J]. Carlsberg research communications, 1985, 50: 309-323.
| Cas No. | 76079-03-3 | SDF | |
| Formula | C16H23N3O5 | M.Wt | 337.38 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.964 mL | 14.8201 mL | 29.6402 mL |
| 5 mM | 592.8 μL | 2.964 mL | 5.928 mL |
| 10 mM | 296.4 μL | 1.482 mL | 2.964 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.50% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)