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BuChE-IN-TM-10 (Synonyms: TM-10)

カタログ番号GC35564

BuChE-IN-TM-10 (TM-10) は強力なブチリルコリンエステラーゼ (BuChE) 阻害剤であり、IC50 は 8.9 nM です。

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BuChE-IN-TM-10 化学構造

Cas No.: 2313524-95-5

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer's disease[1]. IC50: 8.9 nM (BuChE)[1].

[1]. Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.

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