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Donitriptan

カタログ番号GC35894

ドニトリプタンは、それぞれ pKis 9.4 および 9.3 の 5-HT1B/1D 受容体に対する強力で高効能のアゴニストです 。

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Donitriptan 化学構造

Cas No.: 170912-52-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively[1]. 5-HT1B Receptor|9.4 (pKi)|5-HT1D Receptor|9.3 (pKi)

[1]. MuÑoz-Islas E, et al. Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors. Br J Pharmacol. 2006 Sep;149(1):82-91.

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Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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