NSC16168 |
カタログ番号GC36775 |
NSC16168 は ERCC1-XPF の特異的阻害剤であり、IC50 値は 0.42 μM です。 NSC16168 は DNA 修復を阻害し、がんにおける CDDP の有効性を増強します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6837-93-0
Sample solution is provided at 25 µL, 10mM.
NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer[1]. IC50: 0.42 μM (ERCC1-XPF)[1].
[1]. Arora S, et al. Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells. Oncotarget. 2016 Nov 15;7(46):75104-75117.
Average Rating: 5
(Based on Reviews and 11 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *