Quetiapine sulfoxide dihydrochloride |
| カタログ番号GC37057 |
クエチアピン スルホキシド 二塩酸塩 (クエチアピン S-オキシド 二塩酸塩) は、クエチアピネムの主要な代謝産物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 329218-11-3
Sample solution is provided at 25 µL, 10mM.
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Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1].
The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].
[1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
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