Gitoxin |
| カタログ番号GC64887 |
Na+/K+-ATPase 阻害剤である Gitoxin は、通常、Digitoxin の代謝分解の結果として現れ、C-17β 位置に近いヒドロキシル (ZOH) 基にすぎず、薬物動態と薬力学を変化させます。これらの物質のかなり。
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Cas No.: 4562-36-1
Sample solution is provided at 25 µL, 10mM.
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Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably[1].
[1]. Danijela Krstic, et al. Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase. J Enzyme Inhib Med Chem. 2004 Oct;19(5):409-15.
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