Hexanoyl coenzyme A trilithium |
カタログ番号GC67642 |
ヘキサノイル補酵素 A トリチウムは、すべての生物に存在するヘキサノイルベースの中鎖脂肪酸アシル補酵素 A です。ヘキサノイル補酵素 A トリチウムは、カンナビノイド生合成の前駆体として使用でき、中鎖アシル補酵素 A デヒドロゲナーゼ (MCAD) の競合的阻害剤として機能します。
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Cas No.: 103476-19-3
Sample solution is provided at 25 µL, 10mM.
Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD)[1][2].
[1]. Jake M Stout, et al. The hexanoyl-CoA precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in Cannabis sativa trichomes. Plant J. 2012 Aug;71(3):353-65.
[2]. K E Niezen-Koning, et al. Measurement of short-chain acyl-CoA dehydrogenase (SCAD) in cultured skin fibroblasts with hexanoyl-CoA as a competitive inhibitor to eliminate the contribution of medium-chain acyl-CoA dehydrogenase. Clin Chim Acta. 1994 Sep;229
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