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ISIS 104838

カタログ番号GC64767

ISIS 104838 は、関節リウマチの関節痛と腫れの一因となる物質である腫瘍壊死因子(TNF-α)の産生を減少させるアンチセンス オリゴヌクレオチド薬です。

Products are for research use only. Not for human use. We do not sell to patients.

ISIS 104838 化学構造

Cas No.: 250755-32-9

サイズ 価格 在庫数 個数
1 mg
$450.00
在庫あり
5 mg
$990.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

ISIS 104838 is an antisense oligonucleotide drug that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.

[1]. Sewell KL, Geary RS, Baker BF, et al. Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha. J Pharmacol Exp Ther. 2002;303(3):1334-1343.

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