IYPTNGYTR acetate |
| カタログ番号GC63028 |
IYPTNGYTR アセテート、脱アミド感受性シグネチャーペプチドは、トラスツズマブの脱アミド生成物です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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IYPTNGYTR acetate, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR acetate can be used to monitor in vivo Trastuzumab metabolism[1].
IYPTNGYTR is deamidated at pH 7.5 and above, with a higher deamidation rate when the pH increases[1].
[1]. Bults P, et, al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016 Feb 2;88(3):1871-7.
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