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LEESGGGLVQPGGSMK acetate

カタログ番号GC62400

タンパク質分解ペプチドであるLEESGGGLVQPGGSMKアセテートは、インフリキシマブの成分です。

Products are for research use only. Not for human use. We do not sell to patients.

LEESGGGLVQPGGSMK acetate 化学構造

サイズ 価格 在庫数 個数
5 mg
$315.00
在庫あり
10 mg
$549.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

LEESGGGLVQPGGSMK acetate, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK acetate can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

[1]. DorothÉe LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.

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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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