Mal-PEG2-Val-Cit-amido-PAB-OH |
| カタログ番号GC66862 |
Mal-PEG2-Val-Cit-amido-PAB-OH は、抗体薬物複合体 (ADC) の合成に使用される切断可能な ADC リンカーです。 Mal-PEG2-Val-Cit-amido-PAB-OH は、PROTAC の合成に使用できる PROTAC リンカーとしても使用できます。
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Cas No.: 2055041-38-6
Sample solution is provided at 25 µL, 10mM.
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Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-amido-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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