Meclizine N-oxide (Synonyms: Meclozine N-oxide) |
カタログ番号GC49755 |
メクリジンの代謝物
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Cas No.: 114624-69-0
Sample solution is provided at 25 µL, 10mM.
Meclizine N-oxide is a metabolite of the histamine H1 receptor antagonist meclizine .1 It is also a degradation product and potential impurity in commercial preparations of meclizine.2
1.Goenechea, V.S., RÜcker, G., Brzezinka, H., et al.Biotransformation of meclozine in the human bodyJ. Clin. Chem. Clin. Biochem.26(2)105-115(1988) 2.Peraman, R., Manikala, M., Kondreddy, V.K., et al.A stability-indicating RP-HPLC method for the quantitative analysis of meclizine hydrochloride in tablet dosage formJ. Chromatogr. Sci.53(5)793-799(2015)
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