PCLX-001 |
| カタログ番号GC65891 |
PCLX-001 は、経口で活性な低分子のデュアル N-ミリストイルトランスフェラーゼ (NMT) 阻害剤であり、IC50 はそれぞれ 5 nM (NMT1) および 8 nM (NMT2) です。 PCLX-001 は抗腫瘍活性を示し、初期 B 細胞受容体 (BCR) シグナル伝達を阻害し、B 細胞悪性腫瘍の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1215011-08-7
Sample solution is provided at 25 µL, 10mM.
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PCLX-001 is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC50s of 5 nM (NMT1) and 8 nM (NMT2), respectively. PCLX-001 exhibits anti-tumor activity and inhibits early B-cell receptor (BCR) signaling, can be used to B-cell malignancies research[1][2].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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