PF-06928215 |
| カタログ番号GC34712 |
PF-06928215 は、4.9 μM の IC50 を持つ cGAS (サイクリック GMP-AMP シンターゼ) 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2378173-15-8
Sample solution is provided at 25 µL, 10mM.
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PF-06928215 is a cGAS (cyclic GMP-AMP Synthase) inhibitor with an IC50 of 4.9 μμ. PF-06928215 has a high binding affinity of 0.2 μM (KD)[1]. IC50: 4.9 μM (cGAS)[1]
[1]. Hall J, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS One. 2017 Sep 21;12(9):e0184843.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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