Picosulfate (sodium salt hydrate) |
| カタログ番号GC49313 |
刺激性下剤であり、デサセチルビサコジルのプロドラッグ形式です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1307301-38-7
Sample solution is provided at 25 µL, 10mM.
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Picosulfate is a stimulant laxative and prodrug form of desacetyl bisacodyl .1 Unlike bisacodyl , picosulfate is hydrolyzed to DAB by colonic microbiota. Picosulfate (5 mg/kg) increases excreted fecal weight in a rat model of loperamide-induced constipation.2 Formulations containing picosulfate have been used for colonoscopy preparation.
1.Twycross, R., Sykes, N., Mihalyo, M., et al.Stimulant laxatives and opioid-induced constipationJ. Pain Symptom Manage.43(2)306-313(2012) 2.MÉitÉ, S., Bahi, C., YÉo, D., et al.Laxative activities of Mareya micrantha (Benth.) MÜll. Arg. (Euphorbiaceae) leaf aqueous extract in ratsBMC Complement. Altern. Med.107(2010)
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