17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide (Synonyms: 17phenyl trinor PGF2α cyclopropyl methyl amide) |
| カタログ番号GC41970 |
プロスタグランジンF2α（PGF2α）はFP受容体を活性化し、平滑筋の収縮と黄体溶解を促進します。
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Cas No.: 1138395-10-4
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
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