Epibetulinic acid |
| カタログ番号GC60152 |
エピベツリン酸は、細菌エンドトキシンで刺激されたマウス マクロファージ (RAW 264.7) における NO およびプロスタグランジン E2 (PGE2) の産生に対して、それぞれ 0.7 および 0.6 μM の IC50 で強力な阻害効果を示します。
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Cas No.: 38736-77-5
Sample solution is provided at 25 µL, 10mM.
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Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.
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