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Taurohyodeoxycholic Acid

カタログ番号GC41562

タウロヒオデオキシコール酸は、ヒオデオキシコール酸 (HDCA、ジヒドロキシル化天然胆汁酸) のタウロ結合体です。

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Taurohyodeoxycholic Acid 化学構造

Cas No.: 2958/4/5

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1mg
$24.00
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5mg
$105.00
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10mg
$185.00
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25mg
$406.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.

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