RO-7 |
カタログ番号GC32289 |
RO-7 は、インフルエンザ A および B ウイルスの次世代ポリメラーゼ (PA) エンドヌクレアーゼ阻害剤です。
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Cas No.: 1370241-45-4
Sample solution is provided at 25 µL, 10mM.
RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.
RO-7 is a compound that potently inhibits influenza virus replication and belongs to a new class of drugs in late-stage clinical trials for treatment of influenza virus infection. RO-7 displays broad-spectrum anti-influenza activity in vitro and protects mice from lethal challenge with both influenza A and B viruses[1].
RO-7 protects mice from lethal challenge with both influenza A and B viruses[1].
[1]. Jones JC, et al. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation InfluenzaVirus Endonuclease Inhibitors. MBio. 2018 Apr 24;9(2). pii: e00430-18.
Average Rating: 5
(Based on Reviews and 17 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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