Sapienic acid sodium |
| カタログ番号GC61265 |
サピエン酸ナトリウムは、皮膚や粘膜によく見られる脂肪酸です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 217477-25-3
Sample solution is provided at 25 µL, 10mM.
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Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1].
Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h[1].
[1]. Fischer CL, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61.
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