SCF Mouse |
カタログ番号GP20923
One-Click Copy Product Info
|
幹細胞因子マウス再生タンパク質
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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| Purity | ≥ 95% as determined by reducing SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Lyophilized powder | Shipping Condition | Shipped at ice. |
| Synonyms | Kit ligand Precursor; C-kit ligand; SCF; Mast cell growth factor; MGF; SF; KL-1; Kitl; DKFZp686F2250; Hematopoietic growth factor KL; Steel factor. | ||
| Amino Acid Sequence | MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA. | ||
| Formulation | Lyophilized from a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. | ||
Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.The ED50 for this effect is 0.5915 ng/mL, corresponding to a specific activity is 1.69×106 units/mg.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)