SOR-C13 (trifluoroacetate salt) |
| カタログ番号GC52397 |
ペプチドTRPV6アンタゴニスト
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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SOR-C13 is a peptide antagonist of transient receptor potential vanilloid 6 (TRPV6).1 It inhibits calcium flux in HEK293 cells expressing human TRPV6 (EC50 = 14 nM). SOR-C13 (400, 600, and 800 mg/kg) reduces tumor volume in an SKOV3 ovarian cancer mouse xenograft model.
1.Xue, H., Wang, Y., MacCormack, T.J., et al.Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft modelJ. Cancer9(17)3196-3207(2018)
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