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TCMCB07 TFA

カタログ番号GC72308 Copy One-Click Copy Product Info

TCMCB07 TFAはシクロ九ペプチドであり、経口活性と脳透過性黒皮質受容体4(MC 4 R)アンタゴニストである。

Products are for research use only. Not for human use. We do not sell to patients.

TCMCB07 TFA 化学構造

サイズ 価格 在庫数 個数
1 mg
$45.00
在庫あり
5 mg
$135.00
在庫あり
10 mg
$216.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of TCMCB07 TFA

TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia.

References:
[1]. Yongjun Hu, et al. Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1677-1687.

Chemical Properties of TCMCB07 TFA

Cas No. SDF
Formula C63H87N15O11.xC2HF3O2 M.Wt 1230.46 (free base)
溶解度 DMSO : ≥ 100 mg/mL Storage Sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of TCMCB07 TFA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 812.7 μL 4.0635 mL 8.127 mL
5 mM 162.5 μL 812.7 μL 1.6254 mL
10 mM 81.3 μL 406.4 μL 812.7 μL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

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In vivo Formulation Calculator (Clear solution) of TCMCB07 TFA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for TCMCB07 TFA

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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