Tecarfarin |
| カタログ番号GC38857 |
テカルファリン (ATI-5923) は、経口活性で非競合的なビタミン K エポキシド レダクターゼ (VKOR) 拮抗薬であり、ビタミン K 依存性の凝固因子 II、VII、IX、および X の活性化を阻害します 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 867257-26-9
Sample solution is provided at 25 µL, 10mM.
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Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin has the antithrombotic activity [2].
[1]. Hobl EL, et al. Tecarfarin: A Novel Vitamin K Antagonist. Thromb Haemost. 2017 Nov;117(11):2009-2011. [2]. Bowersox SS, et al. Antithrombotic activity of the novel oral anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models. Thromb Res. 2010 Nov;126(5):e383-8.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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