Terpendole C |
| カタログ番号GC45017 |
Albophoma yamanashiensis が産生する Terpendole C は、アシル-CoA: コレステロール アシルトランスフェラーゼ (ACAT) に対して強力な阻害活性を示します 。
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Cas No.: 156967-65-6
Sample solution is provided at 25 µL, 10mM.
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Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes). It also inhibits ACAT in J774 macrophages (IC50 = 0.46 μM) without affecting cell growth.
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