TRAP-6 Peptide (trifluoroacetate salt) (Synonyms: Ser-Phe-Leu-Leu-Arg-Asn, Thrombin Receptor Agonist Peptide-6) |
| カタログ番号GC45073 |
TRAP-6ペプチドは、プロテアーゼ活性化受容体1（PAR1）の残基42〜47に対応する六ペプチドです。
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Sample solution is provided at 25 µL, 10mM.
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TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 µM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
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