Tuberculosis inhibitor 3 |
カタログ番号GC62415 |
結核阻害剤 3 (化合物 2i) は、薬剤感受性/耐性 MTB 株に対して強力な抗結核活性 (MIC < 0.016 μg/mL) を示します。
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Cas No.: 2219325-28-5
Sample solution is provided at 25 µL, 10mM.
Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 µg/mL) against drug-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability[1].
Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) shows acceptable PK properties with the AUC of 2489 h•ng/mL) is. The Tmax of Tuberculosis inhibitor 3 is 0.25 h[1].
[1]. Kai Lv, et al. Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety. Eur J Med Chem. 2018 May 10;151:1-8.
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