>>Signaling Pathways>> Proteases>> Lipoxygenase>>12-epi Leukotriene B4-d4

12-epi Leukotriene B4-d4 (Synonyms: 12epi LTB4d4)

Catalog No.GC46416 Copy One-Click Copy Product Info

A neuropeptide with diverse biological activities

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12-epi Leukotriene B4-d4 Chemical Structure

Cas No.: N/A

Size 가격 재고 수량
25 μg
US$499.00
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50 μg
US$950.00
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100 μg
US$1,798.00
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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of 12-epi Leukotriene B4-d4

12-epi Leukotriene B4-d4 (12-epi LTB4-d4) contains four deuterium atoms at the 6, 7, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 12-epi LTB4 by GC- or LC-mass spectrometry. 12-epi LTB4 is the "unnatural" 12(S) epimer of LTB4. 12-epi LTB4 does not appear in any measurable amount in the LTB4 isomers produced by non-enzymatic hydrolysis of LTA4.1 There are no published reports on the biological activity of 12-epi LTB4.

1.Sala, A., Bolla, M., Zarini, S., et al.Release of leukotriene A4 versus leukotriene B4 from human polymorphonuclear leukocytesThe Journal of Biological Chemisty27117944-17948(1996)

Chemical Properties of 12-epi Leukotriene B4-d4

Cas No. N/A SDF
Synonyms 12epi LTB4d4
Canonical SMILES CCCCC/C([2H])=C([2H])\C[C@H](O)/C=C/C=C/C([2H])=C([2H])\[C@@H](O)CCCC(O)=O
Formula C20H28D4O4 M.Wt 340.5
Solubility DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 12-epi Leukotriene B4-d4

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1 mg 5 mg 10 mg
1 mM 2.9369 mL 14.6843 mL 29.3686 mL
5 mM 587.4 μL 2.9369 mL 5.8737 mL
10 mM 293.7 μL 1.4684 mL 2.9369 mL
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In vivo Formulation Calculator (Clear solution) of 12-epi Leukotriene B4-d4

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for 12-epi Leukotriene B4-d4

Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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