>> Signaling Pathways >> Proteases >> Lipoxygenase

Lipoxygenase

Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid. Thre are six LOX isoforms have been found in the humans and mice. 5-Lipoxygenase (5-LOX) is a distinct isoform playing an important role in asthma and inflammation. 5-LOX causes the constriction of bronchioles in response to cysteinyl leukotrienes such as LTC4, thus leading to asthma. 5-LOX also induces neutrophilic inflammation by its recruitment in response to LTB4. 12-Lipoxygenase (12-LOX) is an isoform expressed in epithelial cells and myeloid cells including platelets. 12-LOX can be found in the epithelial cells of the skin. 12-LOX is a potential target for novel anti-platelet therapeutics.15-Lipoxygenase (15-LOX) is expressed in epithelial cells and leukocytes, has different substrate specificity in the humans and mice.15-LOX-1 is a target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells.

Targets for  Lipoxygenase

Products for  Lipoxygenase

  1. Cat.No. 상품명 정보
  2. GC38000 β-Boswellic acid β-Boswellic acid는 Boswellia serrate의 고무 수지에서 분리됩니다.ޚ-Boswellic acid는 5-lipoxygenase(5-LO) 생성물 형성을 직접 차단하거나 상호작용하는 전위를 차단하는 비환원형 억제제입니다. . β - 보스웰산은 인간 백혈병 HL-60 세포에서 DNA, RNA 및 단백질 합성을 억제합니다. β-Boswellic acid  Chemical Structure
  3. GC41649 (±)13-HODE cholesteryl ester (±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)13-HODE cholesteryl ester  Chemical Structure
  4. GC40828 (±)5-HETE lactone (±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone  Chemical Structure
  5. GC41666 (±)9-HODE cholesteryl ester (±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)9-HODE cholesteryl ester  Chemical Structure
  6. GC41770 1,2,3-Trieicosapentaenoyl-rac-glycerol 1,2,3-Trieicosapentaenoyl-rac-glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid, which is an ω-3 fatty acid. 1,2,3-Trieicosapentaenoyl-rac-glycerol  Chemical Structure
  7. GC45948 1,2,3-Trilinoelaidoyl-rac-glycerol A triacylglycerol 1,2,3-Trilinoelaidoyl-rac-glycerol  Chemical Structure
  8. GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC  Chemical Structure
  9. GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE  Chemical Structure
  10. GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11  Chemical Structure
  11. GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC  Chemical Structure
  12. GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE  Chemical Structure
  13. GC40971 10(S),17(S)-DiHDHA 10(S),17(S)-DiHDHA(신경 조직에서 생성될 때 뉴로프로텍틴 D1이라고도 함)는 DHA에서 파생된 디하이드록시 지방산으로 강력한 보호 및 항염 활성을 나타냅니다. 10(S),17(S)-DiHDHA  Chemical Structure
  14. GC40368 11(R)-HEPE 11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO. 11(R)-HEPE  Chemical Structure
  15. GC40445 11(R)-HETE 11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. 11(R)-HETE  Chemical Structure
  16. GC10821 11-keto-β-Boswellic Acid 11-Keto-beta-boswellic acid(11-Keto-β-boswellic acid)는 인도 유향으로 널리 알려진 Boswellia serrate tree의 껍질에서 추출한 올레오검 수지의 5환형 트리테르펜산입니다. 11-Keto-beta-boswellic acid는 주로 5-lipoxygenase(5-LOX) 및 후속 류코트리엔 및 핵 인자-카파 B(NF-κB) 활성화 및 종양 괴사 인자 알파 생성을 억제하기 때문에 항염증 활성이 있습니다. 생산. 11-keto-β-Boswellic Acid  Chemical Structure
  17. GC41144 11-trans Leukotriene C4 11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. 11-trans Leukotriene C4  Chemical Structure
  18. GC41147 11-trans Leukotriene D4 11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. 11-trans Leukotriene D4  Chemical Structure
  19. GC41149 11-trans Leukotriene E4 11-trans 류코트리엔 E4는 류코트리엔 E4(LTE4)의 이성질체입니다. 11-trans Leukotriene E4  Chemical Structure
  20. GC40447 12(R)-HETE Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. 12(R)-HETE  Chemical Structure
  21. GC40371 12(S)-HEPE 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. 12(S)-HEPE  Chemical Structure
  22. GC40448 12(S)-HETE

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

    12(S)-HETE  Chemical Structure
  23. GC41882 12(S)-HETrE 12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE  Chemical Structure
  24. GC41095 12(S)-HpEPE

    12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid.

    12(S)-HpEPE  Chemical Structure
  25. GC41122 12(S)-HpETE 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. 12(S)-HpETE  Chemical Structure
  26. GC41123 12-epi Leukotriene B4 Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. 12-epi Leukotriene B4  Chemical Structure
  27. GC41096 12-oxo Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. 12-oxo Leukotriene B4  Chemical Structure
  28. GC46418 12-oxo-13-HOME An oxylipin 12-oxo-13-HOME  Chemical Structure
  29. GC40372 12-OxoETE 12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. 12-OxoETE  Chemical Structure
  30. GC19462 13(R)-HODE 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. 13(R)-HODE  Chemical Structure
  31. GC19463 13(S)-HODE 리놀레산의 15-리폭시게나제(15-LOX) 대사 산물인 13(S)-HODE(13(S)-HODE)는 PPARγ을 활성화하는 내인성 리간드로 기능합니다. 13(S)-HODE  Chemical Structure
  32. GC41220 13(S)-HODE methyl ester 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. 13(S)-HODE methyl ester  Chemical Structure
  33. GC41896 13(S)-HODE-biotin 13(S)-HODE is the lipoxygenase metabolite of linoleic acid. 13(S)-HODE-biotin  Chemical Structure
  34. GC46420 13(S)-HODE-d4 An internal standard for the quantification of 13-HODE 13(S)-HODE-d4  Chemical Structure
  35. GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. 13(S)-HOTrE  Chemical Structure
  36. GC41898 13(S)-HOTrE(γ) 13(S)-HOTrE(γ) is the 15-LO product of γ-linolenic acid. 13(S)-HOTrE(γ)  Chemical Structure
  37. GC19474 13(S)-HpODE 13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,1,2 and by 15-LO in mammals. 13(S)-HpODE  Chemical Structure
  38. GC41899 13(S)-HpOTrE

    13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.

    13(S)-HpOTrE  Chemical Structure
  39. GC41900 13(S)-HpOTrE(γ) 13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. 13(S)-HpOTrE(γ)  Chemical Structure
  40. GC41911 13-epi-12-oxo Phytodienoic Acid 13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. 13-epi-12-oxo Phytodienoic Acid  Chemical Structure
  41. GC41206 14(S)-HDHA 14(S)-HDHA(14(S)-HDoHE)는 도코사헥사엔산(DHA)의 산소화 생성물입니다. 14(S)-HDHA  Chemical Structure
  42. GC41100 14,15-dehydro Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. 14,15-dehydro Leukotriene B4  Chemical Structure
  43. GC41145 14,15-Leukotriene C4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene C4  Chemical Structure
  44. GC41148 14,15-Leukotriene D4 14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-Leukotriene D4  Chemical Structure
  45. GC41150 14,15-Leukotriene E4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene E4  Chemical Structure
  46. GC41415 15(R)-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

    15(R)-Lipoxin A4  Chemical Structure
  47. GC40427 15(S)-HEDE 15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE  Chemical Structure
  48. GC40373 15(S)-HEPE 15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. 15(S)-HEPE  Chemical Structure
  49. GC40451 15(S)-HETE 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE  Chemical Structure
  50. GC41925 15(S)-HETE Ethanolamide Arachidonoyl ethanolamide was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. 15(S)-HETE Ethanolamide  Chemical Structure
  51. GC40839 15(S)-HETE methyl ester 15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE methyl ester  Chemical Structure
  52. GC46442 15(S)-HETE-d8 An internal standard for the quantification of 15-HETE 15(S)-HETE-d8  Chemical Structure
  53. GC49894 15(S)-HETE-d8 ethyl ester An internal standard for the quantification of 15(S)-HETE ethyl ester 15(S)-HETE-d8 ethyl ester  Chemical Structure
  54. GC41927 15(S)-HETrE 15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. 15(S)-HETrE  Chemical Structure
  55. GC41403 15(S)-HpEDE

    15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid.

    15(S)-HpEDE  Chemical Structure
  56. GC41101 15(S)-HpEPE

    15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid.

    15(S)-HpEPE  Chemical Structure
  57. GC41124 15(S)-HpETE

    15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid.

    15(S)-HpETE  Chemical Structure
  58. GC41938 15-Lipoxygenase Inhibitor 1 15-리폭시게나제 억제제 1은 IC50이 18 μ인 15-리폭시게나제의 선택적 억제제입니다. 15-리폭시게나제 억제제 1은 IC50이 각각 19.5 μM 및 19.1 μM입니다. 대두 15-리폭시게나제(SLO) 및 인간 15-리폭시게나제-1(15)-LOX-1(15)- 15-Lipoxygenase Inhibitor 1은 전립선암 연구에 잠재력이 있습니다. 15-Lipoxygenase Inhibitor 1  Chemical Structure
  59. GC41940 15-OxoEDE 15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE  Chemical Structure
  60. GC40376 15-OxoETE 15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE. 15-OxoETE  Chemical Structure
  61. GC41951 17(R)-Resolvin D1

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

    17(R)-Resolvin D1  Chemical Structure
  62. GC41227 17(R)-Resolvin D1 methyl ester 17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-Resolvin D1 methyl ester  Chemical Structure
  63. GC41952 17(R)-Resolvin D4 17(R)-Resolvin D4 (17(R)-RvD4) is an aspirin-triggered epimer of RvD4 . 17(R)-Resolvin D4  Chemical Structure
  64. GC41208 17(S)-HDHA 17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA  Chemical Structure
  65. GC49356 17(S)-HDoTE A metabolite of adrenic acid 17(S)-HDoTE  Chemical Structure
  66. GC40975 17(S)-HpDHA 17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA  Chemical Structure
  67. GC41529 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid  Chemical Structure
  68. GC41209 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid  Chemical Structure
  69. GC41980 18-carboxy dinor Leukotriene B4 18-carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4. 18-carboxy dinor Leukotriene B4  Chemical Structure
  70. GC46057 2,5-Dihydroxycinnamic Acid phenethyl ester An inhibitor of 5-LO 2,5-Dihydroxycinnamic Acid phenethyl ester  Chemical Structure
  71. GC42082 20-carboxy Leukotriene B4 20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-carboxy Leukotriene B4  Chemical Structure
  72. GC41421 20-hydroxy Leukotriene B4 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-hydroxy Leukotriene B4  Chemical Structure
  73. GC49849 3-Aminosalicylic Acid A salicylic acid derivative 3-Aminosalicylic Acid  Chemical Structure
  74. GC49364 3-Hydroxycoumarin 3-하이드록시쿠마린은 인간 15-LOX-1의 강력한 산화환원 억제제입니다. 3-Hydroxycoumarin  Chemical Structure
  75. GC64078 3-O-Acetyl-11-hydroxy-beta-boswellic acid 3-O-아세틸-11-하이드록시-베타-보스웰산은 강력한 5-리폭시게나제(5-LO) 억제제입니다. 3-O-Acetyl-11-hydroxy-beta-boswellic acid  Chemical Structure
  76. GC30277 4',5-Dihydroxyflavone 4',5-디하이드록시플라본은 대두 LOX-1 및 효모 α-글루코시다아제 억제제로서 대두 LOX-1의 Ki는 102.6μM이고 효모 α-글루코시다아제의 IC50은 66μM입니다. 4',5-Dihydroxyflavone  Chemical Structure
  77. GC64621 4-Nitrocatechol 4-Nitrocatechol은 강력한 리폭시게나제 억제제입니다. 4-Nitrocatechol  Chemical Structure
  78. GC40459 5(R)-HETE 5(R)-HETE is a rare lipoxygenase product of arachidonic acid. 5(R)-HETE  Chemical Structure
  79. GC41126 5(S),12(S)-DiHETE 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid. 5(S),12(S)-DiHETE  Chemical Structure
  80. GC41127 5(S),15(S)-DiHETE 5(S),15(S)-DiHETE는 \5(S),15(S)-DiHETE is an “activated” intermediate, inhibits platelet aggregation with an IC50 of 1.3 μM.en_ko_2021q1.md 5(S),15(S)-DiHETE  Chemical Structure
  81. GC41128 5(S),6(R)-11-trans DiHETE 5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE  Chemical Structure
  82. GC41129 5(S),6(R)-DiHETE 5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). 5(S),6(R)-DiHETE  Chemical Structure
  83. GC41131 5(S),6(S)-DiHETE 5(S),6(S)-DiHETE is one of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4. 5(S),6(S)-DiHETE  Chemical Structure
  84. GC40378 5(S)-HEPE 5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA). 5(S)-HEPE  Chemical Structure
  85. GC40460 5(S)-HETE 5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE  Chemical Structure
  86. GC40829 5(S)-HETE lactone 5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. 5(S)-HETE lactone  Chemical Structure
  87. GC46679 5(S)-HETE-d8 An internal standard for the quantification of 5-HETE 5(S)-HETE-d8  Chemical Structure
  88. GC42479 5(S)-HETrE 5(S)-HETrE is produced by the action of 5-LO when mead acid is the substrate. 5(S)-HETrE  Chemical Structure
  89. GC41105 5(S)-HpEPE 5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA. 5(S)-HpEPE  Chemical Structure
  90. GC40784 5(Z),8(Z),14(Z)-Eicosatrienoic Acid 5(Z),8(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid that can be a substrate for 5-lipoxygenase (5-LO). 5(Z),8(Z),14(Z)-Eicosatrienoic Acid  Chemical Structure
  91. GC40830 5,6-dehydro Arachidonic Acid 5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. 5,6-dehydro Arachidonic Acid  Chemical Structure
  92. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7  Chemical Structure
  93. GC31997 5-Lipoxygenase-In-1 5-리폭시게나제-In-1은 특허 EP 331232 A2, 표 4, 화합물 실시예 4.10에서 추출한 5-리폭시게나제 억제제입니다. 5-Lipoxygenase-In-1  Chemical Structure
  94. GC66031 5-LOX-IN-1 5-LOX-IN-1(화합물 2b)은 IC50 값이 2.3 μ인 인간 5-Lipoxygenase(5-LOX)의 억제제입니다. 821d96072c2d58d8970e76f526b0f6b85-LOX-IN-1은 염증 연구에 사용할 수 있습니다.821d96072c2d58d8970e76f526b0f6b8 5-LOX-IN-1  Chemical Structure
  95. GC35168 5-O-Demethylnobiletin 5-O-Demethylnobiletin(5-Demethylnobiletin)은 Sideritis tragoriganum에서 분리된 폴리메톡시플라본으로 COX-2의 발현에 영향을 미치지 않으면서 5-LOX(IC50=0.1μM)를 직접적으로 억제합니다. 5-O-Demethylnobiletin  Chemical Structure
  96. GC40380 5-OxoETE

    5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.

    5-OxoETE  Chemical Structure
  97. GC41322 5-OxoETE methyl ester 5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE. 5-OxoETE methyl ester  Chemical Structure
  98. GC41424 6(S)-Lipoxin A4 The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. 6(S)-Lipoxin A4  Chemical Structure
  99. GC46732 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid A metabolite of DPA with antiinflammatory properties 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid  Chemical Structure
  100. GC40978 7-epi Maresin 1 7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1, which contains a 7(R) hydroxyl group. 7-epi Maresin 1  Chemical Structure
  101. GC40462 8(R)-HETE 8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. 8(R)-HETE  Chemical Structure

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