3-Demethylcolchicine (Synonyms: (–)-3-Demethylcolchicine) |
| Catalog No.GC62794 |
콜히친 대사 산물인 3-Demethylcolchicine은 라디칼 소거에 참여할 수 있는 탄소 고리에 히드록시기를 갖고 있으며 카라기닌 부종을 현저하게 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7336-33-6
Sample solution is provided at 25 µL, 10mM.
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3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema[1][2].
[1]. Modriansky M, et al. Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants•. Toxicology. 2002;177(1):105-117.
[2]. Sugio K, et al. Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congeners. Life Sci. 1987;40(1):35-39.
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