3-Demethylcolchicine (Synonyms: (–)-3-Demethylcolchicine) |
| カタログ番号GC62794 |
コルヒチン代謝産物である 3-デメチルコルヒチンは、その炭素環にヒドロキシ基を持っています。これはラジカル スカベンジングに関与し、カラゲニン浮腫を著しく阻害します 。
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Cas No.: 7336-33-6
Sample solution is provided at 25 µL, 10mM.
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3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema[1][2].
[1]. Modriansky M, et al. Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants•. Toxicology. 2002;177(1):105-117.
[2]. Sugio K, et al. Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congeners. Life Sci. 1987;40(1):35-39.
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