(3R,4R)-A2-32-01 |
| Catalog No.GC39179 |
(3R,4R)-A2-32-01(화합물 24(R,R)), A2-32-01의 (R,R)-거울상 이성질체는 황색 포도상구균 카제인분해 프로테아제(SaClpP) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1359752-95-6
Sample solution is provided at 25 µL, 10mM.
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(3R,4R)-A2-32-01 (compound 2), an anti-virulence drug, is a specific caseinolytic protein proteases (ClpP) inhibitor with an EC50 of 4.5 μM, and shows a tolerable cytotoxicity[1].
[1]. Zeiler E, et al. Development and characterization of improved β-lactone-based anti-virulence drugs targetingClpP. Bioorg Med Chem. 2012 Jan 15;20(2):583-91.
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