4-Diethylaminobenzaldehyde (Synonyms: DEAB) |
| Catalog No.GC39245 |
4-Diethylaminobenzaldehyde는 ALDH1의 Ki가 4nM인 가역적 알데히드 탈수소효소(ALDH) 억제제입니다. 4-Diethylaminobenzaldehyde는 강력한 항 안드로겐 효과를 나타냅니다(IC50= 1.71μM).
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Cas No.: 120-21-8
Sample solution is provided at 25 µL, 10mM.
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4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM)[1][2].
[1]. Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1. ACS Chem Biol. 2015 Mar 20;10(3):693-7. [2]. Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19(6):831-42.
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